shilpa gupta linkedin

Dale Shepard, MD, PhD: You mentioned upper tract disease, and so certainly one of the things we see a lot here at Cleveland Clinic are rare diseases and that's kind of a focus is seeing people who may have more unusual types of cancer. View Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. Yeah, absolutely. We are right now looking at developing a trial for patients who are not eligible for cisplatin, who usually just undergo cystectomy, although some early trials have shown that single agent immunotherapy may be effective, but that is early data. Fellowship - Jefferson Medical College of Thomas Jefferson University So any time we open a trial, we are sending out mass emails, and that has been helpful so far. See the complete profile on LinkedIn and discover Shilpa’s connections and jobs at similar companies. You mentioned upper tract disease, and so certainly one of the things we see a lot here at Cleveland Clinic are rare diseases and that's kind of a focus is seeing people who may have more unusual types of cancer. Shilpa has 1 job listed on their profile. Subscribe to the podcast on iTunes, GooglePlay, Spotify, SoundCloud, or wherever you listen to podcasts. 2007, Internship - RCH Government Hospital Shilpa Gupta, MD: Yes, absolutely. 2001, Medical Education - Lady Hardinge Medical College That's an excellent question, Dale. CORONAVIRUS: DELAYS FOR ROUTINE SURGERIES, VISITOR RESTRICTIONS + COVID-19 TESTING. What was the key to the success in getting this trial to happen? Our patients here know that in any case, even if they don't go on a trial, 12 weeks of chemotherapy is standard, and after that, within six to eight weeks, they get operated upon. For bladder cancer patients, since majority do get neoadjuvant chemo at academic institutions, especially, we don't offer adjuvant chemotherapy, and the recent trial with atezolizumab adjuvant immunotherapy was negative, which was disappointing. See the complete profile on LinkedIn and discover Shilpa’s connections and jobs at similar companies. Im Profil von Shilpa Gupta sind 3 Jobs angegeben. Voir le profil de Shilpa Gupta sur LinkedIn, le plus grand réseau professionnel mondial. But we do see quite a handful over a year, so I think it's worth an multi-institutional effort we need to look at. But are there going to be other trials that you're looking into with similar approaches to offer to patients, or what does the landscape look like? For our GU group, we have several lists for everybody out in the community, including urologists and medical oncologists. Shilpa has 6 jobs listed on their profile. See the complete profile on LinkedIn and discover SHILPA’S connections and jobs at similar companies. More recently at the annual ASCO meeting, we saw that in the maintenance setting in metastatic urothelial cancer, patients who get first-line platinum-based chemotherapy, which is the current standard, anybody who progresses after that, we already have single agent immunotherapy approved. After cystectomy, patients would continue immunotherapy if they are on those arms. View Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. Are they leery to enroll in trials that delay surgery? WI USA Shilpa has 8 jobs listed on their profile. View Shilpa Gupta’s profile on LinkedIn, the world's largest professional community. Shilpa Gupta, MD: Yeah, I think the team here is really fantastic. Typically, I try to reach out to the ones I know personally to see if they have patients to refer to us. Shilpa has 1 job listed on their profile. We have the cohort of our trial, the BLASST-1, which is immunotherapy and chemotherapy and Dr. Peter Black, who's a collaborator from Vancouver, he has a cohort of his patients who received only gem-cis chemotherapy and Dr. Andrea Necchi from Italy has done single-agent pembrolizumab trial in the same setting. India Hematology-Oncology Philadelphia, My urology colleagues, especially Dr. Konety, who was the chair there and Dr. Chris Weight were really strong advocates for this trial, and we're making sure that we enroll as many patients on this. Public Health Service-Reportable Financial Conflicts of Interest. Thanks for the opportunity. That's an excellent question, Dale. Shilpa Gupta, MD: Yes. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. As of 1/6/2021, Dr. Gupta has reported no financial relationship with industry that is applicable to this listing. What about the more unusual histologies? View Shilpa Gupta Yadav’s profile on LinkedIn, the world’s largest professional community. Shilpa has 2 jobs listed on their profile. Have a great day. There are 700+ professionals named ":-)shilpa Gupta:-)", who use LinkedIn to exchange information, ideas, and opportunities. Shilpa has 2 jobs listed on their profile. View Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. Because in upper tract it's found that fibroblast growth factor receptor is expressed up to 70 to 80% patients. Cancer Advances, a Cleveland Clinic podcast for medical professionals, exploring the latest innovative research and clinical advances in the field of oncology. View Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. Please join us again soon. New Delhi, Yeah, I think the team here is really fantastic. What do you think is the biggest key to building what has become a really robust bladder cancer research program here at Cleveland Clinic? Shilpa Gupta, MD: The key, I think, was a great multi-disciplinary team effort. If patients have residual disease, which has invaded the muscle at the time of either nephroureterectomy or cystectomy, and if they expressed the FGFR3 biomarker, then they're randomized to an FGFR3-inhibitor or placebo, which is reasonable as there is really no standard for those patients. 2011, Fellowship - Jefferson Medical College of Thomas Jefferson University All the urology colleagues, radiation oncology colleagues, Dr. Mian, who actually is leading another Department of Defense TTSA grant this year, and I'm the co-PI on that along with Dr. Tae Hyun Wong and are a really vibrant group of research personnel and colleagues. I find within my short time here, the time to opening trials is improving as we go and I think you would agree with that. In that trial, we are prospectively selecting based on the biomarker. Do we do that for other diseases? Shilpa has 8 jobs listed on their profile. Dr. Gupta shares data from the phase II Bladder Cancer Signal Seeking Trial (BLASST-1), recently presented at the American Society of Clinical Oncology’s Genitourinary Cancers Symposium. Dale Shepard, MD, PhD: Yeah, absolutely. This was an investigator-initiated trial that I led. Her research work has been published in peer-reviewed journals including the Journal of Clinical oncology, Lancet Oncology, Clinical cancer Research , European oncology, among others. Are they leery to enroll in trials that delay surgery? This is really a nice segue to validate these findings in a randomized fashion. How do you see this moving forward? View Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. View Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. Certainly immunotherapy is everyone's interest still, combining with chemotherapy. That concern, I would say, is not a factor at all. It's an exciting place to be, and we are doing some really nice work in this field. Subscribe to the podcast on iTunes, GooglePlay, Spotify, SoundCloud, or wherever you listen to podcasts. 2008, Residency - University of Connecticut Health Center Shilpa Gupta, M.D. Shilpa Gupta has 2 jobs listed on their profile. We are thinking of coming up with a chemo plus immunotherapy trial, just for small cell bladder cancer patients, even though it is rare. Hematology-Oncology Milwaukee, Shilpa, can you tell me a little bit about your role here at Cleveland Clinic? As you noted, this is a Bladder Cancer Signal Seeking Trial I. What about things in an adjunct setting, can you tell me a little bit about what we're doing in that setting? It does seem to be a common question, doesn't it? More importantly, the combination was very safe with no increased toxicities from the combination. Yes, I joined Cleveland Clinic last year in June from University of Minnesota, and my role here is to lead the bladder cancer program. See the complete profile on LinkedIn and discover Shilpa’s connections and jobs at similar companies. Shilpa Gupta, MD: Yes, absolutely. Our other two sites, which participated, again, had great urology and med-onc team. Internal Medicine Farmington, How about patients? Yeah. Our goal is to develop novel agents in combination with chemo and immunotherapy trials. Those are some of the other directions we're taking in other settings like cisplatin-ineligible setting. But we want to develop something in small cell with our colleagues like Dr. Omar Mian from rad-onc, who has interest in that as a basic scientist. See the complete profile on LinkedIn and discover shilpa’s connections and jobs at similar companies. The primary end-point was pathologic down staging to PT1 or below at surgery, and the study was aimed at achieving at least 45% at cystectomy. Thank you for joining us for another episode of Cancer Advances. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page. View Dr. Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. CORONAVIRUS: DELAYS FOR ROUTINE SURGERIES, VISITOR RESTRICTIONS + COVID-19 TESTING. Thank you for listening. Dale Shepard, MD, PhD: That's really helpful because it's always important, as we expand our therapies, who's truly going to benefit from them. Dale Shepard, MD, PhD: How do you see this moving forward? But we do. Shilpa Gupta, MD: But we do. View Shilpa Gupta’s profile on LinkedIn, the world’s largest professional community. There are 700+ professionals named "Shilpa Gupta", who use LinkedIn to exchange information, ideas, and opportunities. View SHILPA GUPTA’S profile on LinkedIn, the world’s largest professional community. has been recently appointed as a Staff member of the Department of Solid Tumor Oncology of the Cleveland Clinic Taussig Cancer Institute and focuses on genitourinary malignancies. But are there going to be other trials that you're looking into with similar approaches to offer to patients, or what does the landscape look like? Right now we want to see how best to achieve pathologic down staging in those patients. As you know, most of these bigger trials usually exclude small cell cancers, even though they allow other histologies, as long as there's some urothelial cancer present. See the complete profile on LinkedIn and discover Shilpa’s connections and jobs at similar companies. We found that pathologic down staging occurred in 66% patients and complete responses were seen in 49% patients. Are a lot of exciting things going on in bladder cancer research program here at Clinic... 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